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Cellular assays

Determination of cytotoxicity

In vitro testing Cellular assays

Background of cytotoxicity

Determining the cytotoxic activity of an ingredient or molecule in preclinical studies is done to evaluate its safety profile.
By testing a new compound on various cell lines (e.g., liver, kidney, or heart cells), highly toxic molecules can quickly be identified.
Using different cell types, one can predict which organs might be susceptible to damage. For example, a compound that is highly cytotoxic to a liver cell line might indicate a risk of hepatotoxicity in a living organism.

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