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Find out more on articles related to dermocosmetics, nutraceuticals and health

The microbiome and breast cancer: current knowledge & future prospects

In France, breast cancer is the most common and also the deadliest form of cancer among women. That is why, every year, the month of October reminds us of the importance of prevention and screening, which play a vital role in the fight against this disease.

Antimicrobial Resistance

From Global AMR Priorities to Preclinical Reality: Reflections from GAMRIC 2026

Reflections on the WHO session at GAMRIC 2026 and how Target Product Profiles can guide the experimental choices that connect antibacterial innovation with clinical need.

Bacteria

C. acnes's passport

C. acnes is a commensal bacterium essential to skin health… But it can turn into a true opportunistic pathogen as soon as the balance of the microbiome is disrupted.

Dermocosmetics / Nutraceuticals

The microbiome and its role in psoriasis

Psoriasis is not just a skin condition. It is estimated that nearly 125 million people worldwide have psoriasis. In recent years, the link between the microbiome and psoriasis has been increasingly recognised.

Dermocosmetics / Nutraceuticals

The impact of UV rays on the skin microbiome

The human skin is home to a multitude of commensal microorganisms (bacteria, fungi, viruses, parasites) that make up the skin microbiome. This collection of microorganisms interacts with skin cells and immune system cells to maintain skin homeostasis. At the same time, the human skin and its microbiome are subject to external and environmental stressors, such as ultraviolet light (UV).

Fungi

Dandruff: why Malassezia is not the only answer

Dandruff remains one of the most common scalp conditions worldwide, affecting a large proportion of adults regardless of ethnic background. For years, it has been mainly associated with Malassezia overgrowth. Yet recent evidence shows that dandruff is more complex than a simple fungal imbalance.

Dermocosmetics / Nutraceuticals

The scalp microbiome

We often talk about the gut or skin microbiome but tend to overlook the one on our scalp. And yet, this unique ecosystem plays a crucial role in the health of our scalp: an imbalance can lead to complications.

Antimicrobial Resistance

In Armor Project

IN-ARMOR is a European research project funded by HADEA, whose main objective is to combat antimicrobial resistance, one of the greatest threats to global health today, an ambition shared with Vibiosphen.

Antimicrobial Resistance

The Role of Biofilms in AMR

Most bacteria live in the form of biofilms, that is, aggregated communities of microorganisms with a complex architecture, encapsulated within a network of hydrated polysaccharides and DNA. The formation of these biofilms confers substantial robustness to bacteria. Indeed, biofilm-associated infections are particularly problematic due to antimicrobial resistance.

Dermocosmetics / Nutraceuticals

Role of the microbiome in Atopic Dermatitis

Atopic dermatitis is a chronic inflammatory skin disease characterized by intense itching and recurrent lesions. Nowadays, it’s considered one of the most common chronic diseases, affecting up to 20% of children and approximately 10% of adults. AD is now understood as a complex and multifactorial disease. It includes genetic abnormalities, alterations of the epidermal barrier, and an imbalance of the cutaneous microbiota. In this context, the study of the microbiome emerges as a central focus, as it's now clearly established that dysbiosis plays an important role in the pathogenesis of AD and its severity.

Fungi

Why Candida albicans Septicemia Models Have Become Essential in Infectious Disease Research

In the ongoing struggle against infectious diseases, while viruses and bacteria often take center stage, invasive fungal infections represent a silent but growing threat to global health. The emergence of antifungal-resistant strains and the high mortality rates associated with systemic candidiasis make the development of relevant preclinical models critical.

Dermocosmetics / Nutraceuticals

The cutaneous microbiome: a lever in acne treatment

Vulgar acne is a common inflammatory skin disorder of the pilosebaceous unit. It’s characterized by seborrhea and abnormalities in follicular keratinization. Today, acne is recognized as a multifactorial condition, with a high prevalence among young adults. Among the various factors involved in acne, one actor is attracting increasing interest: skin microbiota.

Fungi

Malassezia restricta passport

The Malassezia genus includes several species of yeast that are naturally present on the skin. These yeasts have recently undergone significant taxonomic revisions and are attracting considerable interest in human and animal pathology. Among them are M. globosa, M. furfur, and M. restricta, which we will focus on in this review.

Infectious Diseases

Why Humanized Mouse Models Have Become Essential in Infectious Disease Research

In the ongoing struggle against infectious diseases, the demand for translationally relevant preclinical models has never been greater. The advent of humanized mouse models, engineered to carry functional human genes, tissues, or immune systems, has fundamentally transformed the way we investigate pathogen biology and host responses.

Infectious Diseases

LPS: A Hidden Variable with Major Consequences in Murine Infection Models

In the realm of animal models used for studying infectious diseases, the mouse has established itself as a methodological standard. Yet, at the heart of these studies, a discreet but powerful molecule can undermine results: lipopolysaccharide, or LPS.

Dermocosmetics / Nutraceuticals

Prebiotics and Microbiota Modulation: Murine Validation and Preclinical Solutions at Vibiosphen

Imagine a hidden community, nestled deep within the gut, made up of billions of microorganisms. This vast and invisible population, our microbiota, communicates in a language of chemical signals, metabolites, and subtle ecological balances. And prebiotics?

One Health

How AI Is Disrupting Microbiology and Transforming Preclinical Models

In recent years, artificial intelligence (AI) has rapidly become a cornerstone of innovation in life sciences. But while headlines often focus on its use in radiology or drug discovery, a quieter revolution is taking place in microbiology, one that may prove just as transformative, particularly for preclinical research in infectious diseases.

Fungi

Killer Fungi and Climate Change: When Science fiction Becomes Reality

Climate change is not only reshaping our environment, it’s also accelerating the spread of infectious diseases, including dangerous fungal pathogens.

Virus

Influenza B: A Silent Threat with Heavy Consequences

While seasonal flu is often spoken of as a single entity, Influenza B tends to remain in the shadow of its cousin, Influenza A, yet its health and economic burden is far from negligible. Did you know that Influenza B accounts for nearly one-third of seasonal flu cases each year?

Antimicrobial Resistance

How Antimicrobial Resistance and Climate Change Intertwine: A Call for One Health Solutions

Effective management of AMR and CC demands robust economic and political actions. Global and national plans should be aligned to address these interconnected challenges. Policies need to encourage the responsible use of antimicrobials and foster environmental sustainability.

Antimicrobial Resistance

Harnessing AI and Global Innovation to Combat Antimicrobial Resistance

In the face of escalating antimicrobial resistance (AMR), researchers and innovators are turning to advanced technologies like Artificial Intelligence (AI) and genomic sequencing to pave new roads in the battle against superbugs.

Antimicrobial Resistance

Leveraging Preclinical Innovations to Combat Antimicrobial Resistance: Lessons from the Montreal Protocol

In the wake of the upcoming UN General Assembly, the spotlight turns to a pressing global health challenge: antimicrobial resistance (AMR).

Bacteria

Escherichia coli passport

Escherichia coli, commonly referred to as E. coli, is a familiar term to many. It is a rod-shaped bacterium that is typically found in the lower intestines of warm-blooded organisms, including humans.

Bacteria

Bacteria Communication: The Intricate World of Quorum Sensing

Bacteria rely on a system called quorum sensing (QS) to sense population density and make collective decisions.

Antimicrobial Resistance

EU Horizon Grant to fund the fight against AMR - IN-ARMOR project

The 6M € granted to IN-ARMOR project will optimize an already developed drug platform using Computer Aided Drug Design.

Infectious Diseases

An innovative tool to boost preclinical development

Vibiosphen’s constant objective is to develop innovative and translational experimental models that would ultimately result in the decrease of the number of animals used for preclinical testings.

Antimicrobial Resistance

Resistance, Tolerance & Persistence

By zooming in the mechanism that bacteria use to escape the antibiotics, we find three different subgroups – resistance – tolerance – persistence. Distinguishing these three groups is key in the fight against bacterial infection.

Bacteria

Malassezia restricta involvement in dandruff pathology

A collaboration between 3 players : L’oréal – Qima – Vibiosphen. Our last collaboration led to a great publication to understand the aetiology of dandruff, and specifically the role of Malassezia restricta.

Bacteria

C. acnes and extracellular vesicles roles in acne

Acne vulgaris is a common inflammatory disorder affecting more than 80% of young adolescents. Cutibacterium acnes plays a role in the pathogenesis of acne lesions, although the mechanisms are poorly understood.

Dermocosmetics / Nutraceuticals

Atopic dermatitis and the gut skin axis mice model

Recent advances in sequencing technology have demonstrated that the development of AD not only associates with the skin microbiome, but also with gut microbiota. In other words, unbalanced gut microbiome or intestinal permeability may lead to a loss of integrity of the skin barrier that might trigger predispositions to atopic dermatitis in this case.

Infectious Diseases

Organoids: The underrated roles they played during the pandemic

Organoids are miniaturized in vitro organ models that are derived from stem cells. They can be established from two sources of cells: adult stem cells (ASCs) or induced pluripotent stem cells (iPSCs). The organoids are formed by generating 3D aggregate through the cell culture.

Antimicrobial Resistance

Cystic fibrosis associated bacterial resistance

Cystic fibrosis is an inherited disease that causes a buildup of thick mucus in the lungs, leading to repeated bacterial infections that damage the lungs and can cause respiratory failure. Adding to this problem when the bacterial infection become resistant bacteria the treatment of the patient become really challenging.

Antimicrobial Resistance

The dual side of antibiotics

On the one hand, antibiotics are one of the most powerful tools to save lives. The breakthrough that saved many lives also gets its dark side. Despite the decreasing efficacy in the treatment of patients and the rise of resistance due to the misuse of antibiotics and not of antibiotics themselves, scientists have found a real downside: the impact on the gut microbiota. “a growing number of studies are finding that even a short course of antibiotics can alter the makeup of the bacterial species in the gut.”

One Health

The link between climate change and infectious diseases

A direct link between climate change and infectious diseases can be explained by one notion: the one health concept. As a reminder, the one health concept is a concept that stand for the interconnection of human – animal and environment health. Dysregulating one aspect can have an impact on others. In this specific case, the three notions of health are interconnected. As a consequence of climate change, scientists predict that wild animals will be forced to relocate their habitats and will most likely be closer to human population or to farmed animals.

Infectious Diseases

Development of the COVID-19 infection model: a preclinical study of a new drug Rafamin

A valid animal model of SARS-CoV-2 infection and its complications might shed light on the pathophysiology of the disease and can be used for assessing the efficacy and safety of novel antiviral compounds. At Vibiosphen, we reproduced a mouse model of SARS-CoV-2 infection [1] and modified it to better define key post-infection immunological abnormalities. For this purpose, 7-week-old transgenic (K18-hACE2)2Prlmn male mice were intranasally challenged with a lethal dose (200 PFU/mouse) of SARS-CoV-2 (Wuhan strain).

One Health

Pollution of the world’s rivers, how big is the concern ?

In almost 1 / 4 of the sites monitored worldwide, the concentrations of medicine found in rivers exceed the levels recommended preserving aquatic biodiversity or to prevent antibiotic resistance: that is one of the outcomes of a study performed through the University of York (United Kingdom), in collaboration with 86 studies institutes, including the National Research Institute for Agriculture, Food and the Environment (Inrae) in France.

Bacteria

The problem behind the antimicrobial industry

The silent pandemic threat is now well known in the field of infectious disease, but yet still few new antimicrobials are coming on the market. Even if a recent study showed that in 2019, 1,2 Million death was due to resistant bacterial infections and thus more death was attributed to bacterial infection than HIV or Malaria.

Antimicrobial Resistance

The success story of phage therapy

Antimicrobial resistance (AMR) is often viewed as a concept but not as a reality. Highlighting stories of real-life dramatic patient AMR is essential for sensibilization.

Antimicrobial Resistance

The Silent pandemic's heavy tone

Nowadays, we face the Covid-19 pandemics but under our radar the silent pandemic is rising. It is common to hear about the outbreaks of flu, malaria, or outbreaks from new Covid-19 variant. It is less common to hear about the outbreaks of antimicrobial resistance (AMR) referred as the silent pandemic.

One Health

The One Health concept and its two pillars

The one health concept intends to avoid new pandemics by having a systemic point of view of the situation. We can take the concept as a two pillars solution. On the one hand by controlling the exposition of livestock with wildlife to reduce the cross-contamination and on the other hand by controlling the risk of emerging diseases inside the livestock.

Antimicrobial Resistance

Bacteriocins a potential alternative to antibiotics

Bacteriocins, also known as antimicrobial peptides, are produced naturally by bacteria. Bacteriocins have antimicrobial activity against bacteria closely related to the producer strain in order to protect their ecological niche.

Dermocosmetics / Nutraceuticals

The interaction of gut microbiome and drugs

Drugs have a significant impact on the gut microbiome, but the opposite is also true, gut microbiome has an impact on how the drug fulfills its mission. The onehealth paradigm is once again highlighted as a potential game-changer for treatment efficacy and toxicity elaboration.

Antimicrobial Resistance

The threatening crisis of ESKAPE pathogens

The emergence of bacterial pathogens with acquired resistance to almost all available antimicrobials is one of the major concerns today. Resistant pathogens are causing 700,000 deaths per year. It is expected by 2050 that infectious diseases will be responsible for more than 10 million deaths per year, a number higher than the 8.2 million caused by cancer today.