Antimicrobial Resistance

Antimicrobial resistance at Vibiosphen: articles on biofilms, persisters, new anti-infective strategies and the preclinical models used to test them.

Antimicrobial Resistance

From Global AMR Priorities to Preclinical Reality: Reflections from GAMRIC 2026

Reflections on the WHO session at GAMRIC 2026 and how Target Product Profiles can guide the experimental choices that connect antibacterial innovation with clinical need.

Antimicrobial Resistance

In Armor Project

IN-ARMOR is a European research project funded by HADEA, whose main objective is to combat antimicrobial resistance, one of the greatest threats to global health today, an ambition shared with Vibiosphen.

Antimicrobial Resistance

The Role of Biofilms in AMR

Most bacteria live in the form of biofilms, that is, aggregated communities of microorganisms with a complex architecture, encapsulated within a network of hydrated polysaccharides and DNA. The formation of these biofilms confers substantial robustness to bacteria. Indeed, biofilm-associated infections are particularly problematic due to antimicrobial resistance.

Antimicrobial Resistance

How Antimicrobial Resistance and Climate Change Intertwine: A Call for One Health Solutions

Effective management of AMR and CC demands robust economic and political actions. Global and national plans should be aligned to address these interconnected challenges. Policies need to encourage the responsible use of antimicrobials and foster environmental sustainability.

Antimicrobial Resistance

Harnessing AI and Global Innovation to Combat Antimicrobial Resistance

In the face of escalating antimicrobial resistance (AMR), researchers and innovators are turning to advanced technologies like Artificial Intelligence (AI) and genomic sequencing to pave new roads in the battle against superbugs.

Antimicrobial Resistance

Leveraging Preclinical Innovations to Combat Antimicrobial Resistance: Lessons from the Montreal Protocol

In the wake of the upcoming UN General Assembly, the spotlight turns to a pressing global health challenge: antimicrobial resistance (AMR).

Antimicrobial Resistance

EU Horizon Grant to fund the fight against AMR - IN-ARMOR project

The 6M € granted to IN-ARMOR project will optimize an already developed drug platform using Computer Aided Drug Design.

Antimicrobial Resistance

Resistance, Tolerance & Persistence

By zooming in the mechanism that bacteria use to escape the antibiotics, we find three different subgroups – resistance – tolerance – persistence. Distinguishing these three groups is key in the fight against bacterial infection.

Antimicrobial Resistance

Cystic fibrosis associated bacterial resistance

Cystic fibrosis is an inherited disease that causes a buildup of thick mucus in the lungs, leading to repeated bacterial infections that damage the lungs and can cause respiratory failure. Adding to this problem when the bacterial infection become resistant bacteria the treatment of the patient become really challenging.

Antimicrobial Resistance

The dual side of antibiotics

On the one hand, antibiotics are one of the most powerful tools to save lives. The breakthrough that saved many lives also gets its dark side. Despite the decreasing efficacy in the treatment of patients and the rise of resistance due to the misuse of antibiotics and not of antibiotics themselves, scientists have found a real downside: the impact on the gut microbiota. “a growing number of studies are finding that even a short course of antibiotics can alter the makeup of the bacterial species in the gut.”

Antimicrobial Resistance

The success story of phage therapy

Antimicrobial resistance (AMR) is often viewed as a concept but not as a reality. Highlighting stories of real-life dramatic patient AMR is essential for sensibilization.

Antimicrobial Resistance

The Silent pandemic's heavy tone

Nowadays, we face the Covid-19 pandemics but under our radar the silent pandemic is rising. It is common to hear about the outbreaks of flu, malaria, or outbreaks from new Covid-19 variant. It is less common to hear about the outbreaks of antimicrobial resistance (AMR) referred as the silent pandemic.

Antimicrobial Resistance

Bacteriocins a potential alternative to antibiotics

Bacteriocins, also known as antimicrobial peptides, are produced naturally by bacteria. Bacteriocins have antimicrobial activity against bacteria closely related to the producer strain in order to protect their ecological niche.

Antimicrobial Resistance

The threatening crisis of ESKAPE pathogens

The emergence of bacterial pathogens with acquired resistance to almost all available antimicrobials is one of the major concerns today. Resistant pathogens are causing 700,000 deaths per year. It is expected by 2050 that infectious diseases will be responsible for more than 10 million deaths per year, a number higher than the 8.2 million caused by cancer today.